![]() ![]() An opioid is a drug that produces opioid-like effects through its action on the brain’s mu receptor, regardless of its source. Its leaves contain alkaloids, which are nitrogen compounds classified as opioids. So what is the relationship between kratom and Suboxone? Kratom is a Southeast Asian tree in the coffee family. ![]() These features make Suboxone and excellent choice for MAT or medication-assisted treatment. Buprenorphine activates the mu receptor just enough to suppress opioid drug cravings and withdrawal symptoms. ![]() This is why it doesn’t typically produce a feeling of being high when taken orally as directed, especially compared to such powerful full mu receptor activators like oxycodone and fentanyl. ![]() However, buprenorphine, the synthetic opioid part of Suboxone, is only a partial activator of the mu receptor. Suboxone, a synthetic opioid combination drug containing buprenorphine and naloxone, also binds to the mu opioid receptor. It’s the mu most associated with pain relief, euphoria and opioid withdrawal symptoms. The brain has three main opioid receptors, the mu, the delta and the kappa. Kratom also eases opioid withdrawal considerably, which it likely couldn’t do if it didn’t have at least some binding affinity for the MOR or mu opioid receptor. This is because kratom, a Southeast Asian tree in the coffee family, contains alkaloids known to activate the brain’s opioid receptors. Does Suboxone block kratom? Yes, it probably does, at least to some degree. ![]()
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